“Dang but I hate a vague sense of unease, I mean it is not as bad as acute, specific dread but it is its own special flavor of bad times.” – J. Jacques, Questionable Content comment on cartoon #1847
For the fullest, richest context, I’d recommend reading the entire series of comics from number one to present. If you don’t have a week or so of free time, I think the quote still speaks quite well stand-alone.